starting offense: QB – Jimmy Garoppolo RB – Matt Breida

starting offense:
QB – Jimmy Garoppolo
RB – Matt Breida
FB – Kyle Juszczyk
TE – George Kittle
WR – Emmanuel Sanders
WR – Deebo Samuel
LT – Joe Staley
LG – Laken Tomlinson
C – Ben Garland
RG – Mike Person
RT – Mike McGlinchey